产品货号：
Z16893
中文名称：
GBL/MLST8抗体
英文名称：
Anti-GBL/MLST8 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GBL/MLST8 Antibody |
| 指标别名 | Target of rapamycin complex subunit LST8;TORC subunit LST8;G protein beta subunit-like;Gable;Protein GbetaL;Mammalian lethal with SEC13 protein 8;mLST8;MLST8;GBL;LST8 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | MLST8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | GbL antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human GbL.The immunogen is located within the first 50 amino acids of GBL. |
| 计算分子量 | 36kDa |
| 成分 | GBL Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | GBL Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | GbetaL (G protein beta protein subunit-like) is a member of a signaling pathway that regulates mammalian cell growth in response to the presence of nutrients and growth factors.It binds to the kinase domain of TOR (Target of rapamycin,also known as mTOR),an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors.Rapamycin inhibits TOR resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation.TOR is normally associated with GbetaL and an additional regulatory protein RAPTOR,allowing TOR to control protein biosynthesis.The binding of GbetaL to TOR stimulates TOR's kinase activity towards downstream proteins such as RPS6K (ribosomal protein S6 kinase) and the translation factor 4E-BP1 which leads to increased protein translation and cell growth. |
| Uniprot ID | Q9BVC4 |
| 基因名全称 | G protein beta subunit-like |
| 蛋白名全称 | G protein beta subunit-like |
| 推荐稀释比 | GbL antibody can be used for the detection of GbL by Western blot at 1 and 2μg/mL.Antibody can also be used for immunohistochemistry starting at 10μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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